The data paralleled those in the CRC cell lines and Kras knockdown was demonstrated to inhibit cell motility (PSN1Kras-/evc versus PSN1ssc/evc, p<0.001) whilst this could be rescued by restoration of Cten expression (PSN1Kras-/evc versus PSN1Kras-/GFP-Cten, p<0.001, Figure 5c). Here, KRAS is linked to colorectal carcinoma.