Although most PD patients are idiopathic, 5–10% of PD patients are diagnosed to be linked to certain gene mutations, such as α-synuclein, UCHL1, LRRK2 (Leucine-rich repeat kinase 2), PINK1, Parkin, DJ-1, and ATP13A2[3]. The gene discussed is PRKN; the disease is Parkinson disease.