Of note, among non-IBD controls two patients had diverticulitis and presented expression levels for meprin α (1.6 and 2.4) and β (2.7 and 3.9) close to the median, and one patient had pouchitis but the pouchitis-derived biopsy showed a rather low level for meprin α (0.8) and almost average meprin β expression (2.2). The gene discussed is MEP1B; the disease is inflammatory bowel disease.