In order to analyze HIPK2 protein levels in wt-p53-carriyng WDTCs and to correlate it with Gal-3 protein expression, a total of 43 thyroid lesions from patients of group A, including 14 FHs, 24 PTCs and 5 follicular thyroid carcinomas (FTCs) (Table 1), have been analyzed by immunohistochemistry (IHC) for the expression of HIPK2, p53 and Gal-3 (Table 2). The gene discussed is HIPK2; the disease is Floating-Harbor syndrome.