Dicer expression level was significantly associated with tumor mitotic index (P = 0.04, n = 19) and Breslow's depth of invasion (P = 0.03, n = 19) (Fig. 4A-B-D, Tables 3-4), two of three most important parameters currently used in staging and predicting prognosis for melanoma patients by the American Joint Committee on Cancer (AJCC) [19]. This evidence concerns the gene DICER1 and melanoma.