To this end, we tested a large clinical sample set of formalin-fixed paraffin-embedded (FFPE) benign and malignant tumors (n = 404) including melanocytic nevi (benign melanocytic hyperplasia), a variety of melanoma subtypes (cutaneous, acrolentiginous, mucosal, ocular and desmoplastic), a variety of carcinomas (squamous, basal cell and eccrine) and sarcomas (Table 1) using a monoclonal anti-human Dicer antibody and immunohistochemistry on tissue microarrays (TMAs) (Fig. 1A) and full tumor sections (Fig. S1A-F). The gene discussed is DICER1; the disease is sarcoma.