FRMD3 and type 2 diabetes mellitus: Subsequent analyses revealed that FRMD3 SNP rs942280 (and others) were significantly associated with increased risk for T2DM-ESRD in non-MYH9 E1 risk haplotype homozygotes (rs942280 OR 1.28, 95% CI 1.09–1.51), but not in MYH9 E1 risk allele homozygotes (homozygosity p-value comparing the effect of FRMD3 SNPs in MYH9 E1 non-risk homozygotes vs. MYH9 E1 risk homozygotes = 4.82E−4).