Table 1 displays the numbers in each case and control group that were homozygous for MYH9 E1 risk haplotypes and had 2 APOL1 G1 and/or G2 nephropathy risk variants, along with demographic characteristics. Individuals with the MYH9 E1 haplotype or APOL1 risk variants (homozygous or heterozygous) tended to have greater estimated West African ancestry based on the principal component analysis (PCA) (p-value<1E−4). This evidence concerns the gene APOL1 and Nephropathy.