The FOXO (Forkhead box, class O) is a subfamily of forkhead transcription factor and consists of FOXO1A (FKHR: Forkhead in rhabdomyosarcoma, also known as FOXO1), FOXO3A (FKHR-like 1), MLLT7 (AFX: acute-lymphocytic-leukaemia-1 fused gene from chromosome X, also known as FOXO4) and FOXO6 [1]. Here, FOXO4 is linked to rhabdomyosarcoma.