At 50 μM, Rsv induces release of cytochrome C from the mitochondria, formation of apoptosome, autophagic morphology and loss of membrane integrity in ovarian cancer cells [30], in a mechanism that was not inhibited by Bcl-2 overexpression, suggesting that neither classical apoptosis nor beclin1-dependent autophagy are involved. The gene discussed is CYCS; the disease is ovarian carcinoma.