F11R and neoplasm: Analysis of MMTV-PyVmT tumors showed that in absence of JAM-A, tumor cells proliferate slightly less (27.73±2.29% versus 35.6±2.02, p<0.05) but undergo apoptosis to higher extent than in the presence of this adhesive molecule (96.4±10.2 versus 63.1±8.5 cells per mm2 p<0.05) (Fig. 2A).