Comparison of gene expression profiles of JAM-A+/+ and −/− tumors and the G1–G3 human breast tumor published data [25] shows that genes over expressed by MMTV-PyVmT/JAM-A+/+ mice tumors are also over expressed in human G3 tumors, whereas genes over expressed by JAM-A−/− mice tumors are over expressed in human G1 tumors. This evidence concerns the gene F11R and breast neoplasm.