EPCAM and ovarian neoplasm: The role of EpCAM in ovarian tumour progression, however, is unclear; one study reported that FIGO stage III/IV showed lower EpCAM expression than stage I (Kim et al, 2003), while in another study, FIGO stage III/IV showed higher EpCAM expression than stage I/II disease (Heinzelmann-Schwarz et al, 2004).