Our results observed that GO-Y030 and curcumin could inhibit cell viability of the ALDH+/CD133+ subpopulation from SW480, HCT-116, DLD-1, and HT29 (Figure 4A) colorectal cancer cells, further supporting the idea that this subpopulation of colorectal cancer stem cells is sensitive to GO-Y030. The gene discussed is LDHA; the disease is colorectal cancer.