IL10 and neoplasm: Since IL-12p70 plays a critical role in the effective priming of a TH1 anti-tumor immune response and CTL activities [26,42], and IL-10 has been shown to inhibit the production of IL-12p70 in murine DCs [43,44], we next evaluated the expression and balance of IL-12p70 and IL-10 activities in various TCL-pulsed DC vaccines.