GNLY and infection: Transcripts for granulysin were identified as the most highly up-regulated in immune sheep (+94 fold), compared with naïve at day 5 post-infection (p.i.)(Table 4; Figure 3), and were confirmed to show significantly (FDR ≤ 0.05) highly up-regulated expression in immune animals at all timepoints post-challenge by multiplex qRT-PCR (Figure 4).