TFF3 is IL-4/IL-13-regulated and interacts with the mucin MUC2 (not on array) to alter mucus viscosity, with which it co-localises in human intestinal goblet cells, and up-regulation of both these mucus components has been associated with responses to nematode infection in mice (reviewed by [43]). The gene discussed is MUC5AC; the disease is Nematoda infectious disease.