Albumin values in cases ranged from 2.0-4490 mg/gm creatinine (mean, 1090 mg/gm), but kallikrein and albumin excretions did not correlate (Pearson r = 0.006, p = 0.54), rendering it unlikely that elevated kallikrein activity in AKI arose simply from pathological excretion of plasma proteases. This evidence concerns the gene KLK4 and acute kidney injury.