As manifested in Figure 5, in both SLE patients and normal controls, IFN-λ1-stimulated PBMC emerged higher levels of chemokines IP-10 (P = 0.039, 0.028, Figure 5a) and MIG (P = 0.009, 0.038, Figure 5b) in comparison with positive control LPS, and about the secretion of IL-8, the same result was observed in normal controls (P = 0.049, Figure 5c). Here, IFNL1 is linked to systemic lupus erythematosus.