In consequence, we also assessed the correlation between IFN-λ1 and disease manifestations in patients with SLE; however, we did not distinguish the relationships among serum IFN-λ1 protein levels and alopecia, mucosal ulcer, malar rash, fever, chest affection, neurological disorder, anemia, thrombocytopenia and leucopenia. This evidence concerns the gene IFNL1 and systemic lupus erythematosus.