As a result, for exploring the function mechanism of IFN-λ1 in SLE, we detected the ability of IFN-λ1 to induce PBMC to secret MIG, IP-10 and IL-8 in patients with SLE, recognizing that in patients with SLE, IFN-λ1 had the ability to induce secretion of IP-10, MIG and IL-8. Here, CXCL10 is linked to systemic lupus erythematosus.