A total of 302 probands from Korean families with RP were screened for mutations in RHO. By sequencing the exons and flanking intronic regions, five heterozygous mutations (c.50C>T, p.T17M; c.533A>G, p.Y178C; c.888G>T, p.K296N; c.893C>A, p.A298D; and c.1040C>T, p.P347L) were identified in six probands and were absent in 114 controls (Table 2). This evidence concerns the gene RHO and retinitis pigmentosa 1.