MBP and rheumatoid arthritis: A genome scan of 225,079 SNPs in two DNA collections of RA patients followed by replication in two additional collections led to identification of a novel risk variant, rs2000811 (p = 2.7×10−8, OR 1.23, 95% CI: 1.14–1.32), in the second intron of the MBP gene at chromosome 18q23.