However, all 25 mice from LSL- K-rasG12D; Pdx1-Cre; Ink4a/Arf (we called KCI for this manuscript) group were found to have pancreatic tumors ranging in diameter from 4 to 10 mm between 45 to 80 days (Fig. 1A). Here, CDKN2A is linked to pancreatic neoplasm.