PLA2G3 and lung disorder: Unlike Pla2g5-Tg mice, which die shortly after birth due to a lung disorder resulting from aberrant hydrolysis of the lung surfactant phospholipids (see above), Pla2g3-Tg mice showed no respiratory disorder, and lung surfactant phospholipids did not show appreciable difference between control and Pla2g3-Tg mice [51].