Several genes located on 20q, for example, the oncogenes located on 20q13.1, such as CAS/CSE1L, NABC1, ZNF217, Aurora2 (BTAK, STK15) and the ubiquitin-conjugating enzyme E2C (UBE2C), have been described to have an important role in tumour progression and liver metastases. The gene discussed is CSE1L; the disease is neoplasm.