In addition, basal breast tumors are characterized by low ER and PR expression as well as high levels of EGFR [1,46], elevated expression of AKT3 [56], CD44 and MET [57] and decreased GATA3 expression [1]; features that are also consistent with each of the HER2 related subgroups investigated in the current study. This evidence concerns the gene EGFR and breast neoplasm.