It is noteworthy that elevated levels of IL-6, IL-8, IL-10, G-CSF, and TNF-alpha, which were observed in MACV-infected STAT-1 knockout mice (Figure 3), are correlated with the severity of human Argentinean hemorrhagic fever, caused by the related Junín virus [23-25]. The gene discussed is CSF3; the disease is hemorrhagic fever.