FAP and familial pancreatic carcinoma: Interestingly, our results using MDA-MB-231 cells were comparable to the ones observed with Panc-1, and thus we concluded that fibroblastic FAP-dependent matrix alterations and the importance of β1-integrin in the regulation of cancer cell motility are effects that are not necessarily restricted to pancreatic cancers and that additional cancers such as breast, where stromal FAP expression levels have been shown to be increased [47], show similar behaviors.