To compare our observations of the specific matrix architectures stemming from the FAP matrix series to matrices derived from normal pancreas human stellate cells and activated adenocarcinoma-associated fibroblasts, we proceeded to isolate these two types of human pancreatic fibroblastic cells from matched fresh surgical normal and pancreatic tumor (i.e., adenocarcinoma) samples (see Materials and Methods). The gene discussed is FAP; the disease is pancreatic neoplasm.