FGFR1 and hepatocellular carcinoma: We examined FGFR1 protein expression by immunoblot analysis in 8 primary NSCLC cell lines that harbor focal or broad 8p11 amplification above a log2 ratio of 1.6 or 6.0 normalized DNA copies (NCI-H1703, NCI-H2444, NCI-H520, NCI-1581, NCH-H2077, Calu3, NCI-H1734, and HCC 95), 3 that have approximately neutral FGFR1 copy number (NCI-2170, NCI-H226 and A427) and 3 that harbor FGFR1 deletion (NCI-H1781, NCI-H1563 and HCC15) by immunoblot analysis.