RHOA and Gitelman syndrome: A comparison of the complex's levels and behavior in Bartter's and Gitelman's syndromes, a human model of blunted Ang II signaling system and RhoA-Rho kinase pathway [13,15-18] and activation of Ang II type 2 receptor signaling [19] to the complex's levels and behavior in hypertensive patients, which have Ang II signaling system and RhoA-Rho kinase pathways, biochemical, molecular and clinical features opposite to those of the Bartter's and Gitelman's patients [16], might provide insight into the complex's role in Ang II signaling.