INS and steatosis: There were no significant differences between the two genotype classes in plasma concentration of ALT and AST levels, presence or absence of steatosis, total cholesterol, HDL-and low density lipoprotein (LDL)-cholesterol, circulating triglycerides, surrogate indices of insulin resistance (homeostatic model assessment of insulin resistance and Matsuda Insulin Sensitivity Index), glucose and insulin levels (data not shown).