Diarrhoea, coughing, high blood pressure, always sick, thin, body weakness, headache, change of skin colour, loss of appetite, coughing deep, ulcers around mouth, unexpected weight loss, fever, body sores, impaired vision, loss of appetite, persistent cough, whooping cough, low CD4 count, have STDs most times, pimples around body, skin rashes, swollen glands, swollen skin, syphilis, gonorrhoea, TB, malaria, tired, night sweats, and many opportunistic infections. This evidence concerns the gene CD4 and malaria.