CXCL8 and infection: In contrast, M-T1 was not able to bind or inhibit chemokines of the CXC subfamily, at least as assessed by chemical crosslinking in vitro, such as CXCL8 (ie IL-8, in humans), and this could explain why neutrophils are the dominant early responder leukocytes at sites of infection in experimentally MYXV-infected laboratory rabbits [12,67].