This is reflected by the decreased rate of procedures being performed for abnormal mammographic findings, from 32.4% in 1995 to 16.8% in 2005, and the increase in preoperative diagnoses of breast cancer or pre-malignant lesions such as ADH/ALH from 32.4% in 1995 to 43.1% in 2005. The gene discussed is AVP; the disease is breast cancer.