A study be Onay et al. also concluded that 19 individual commonly occurring SNPs associated with 18 key cancer genes XPD, PTEN, GADD45, p27, ESR1, CYP17, GSTM3, MTHFR, IL1a, IL10, IL13, TNFa, G-CSF, CCND1, COMT, BARD1, GSTP1 and MMP1 did not contribute to breast cancer risk (Onay et al. 2006). The gene discussed is PTEN; the disease is breast cancer.