TXNRD2 and breast cancer: Some borderline significance of SNPs in few selected antioxidant defense genes (for example CAT g27168a, TXN t2715c, TXNRD2 A66S and TXNRD2 g23524a) and epigenetic genes (for example DNMT3b-c31721t) with breast cancer risk has been reported but these observations need to be confirmed in larger epidemiological studies (Cebrian et al. 2006a; Cebrian et al. 2006b).