To test QC cloning with a variety of targets, we cloned the variable regions of the heavy and light chains of immunoglobulins expressed in two non-Hodgkin lymphoma biopsy samples: T109, which contains a tumor-associated immunoglobulin of the isotype IgG,L (heavy chain Gamma, light chain Lambda), and T069, with the isotype IgM,K (heavy chain Mu, light chain Kappa). This evidence concerns the gene CD40LG and neoplasm.