The regions analysed for fine mapping encompassed only a minority of the transcribed and flanking regions of GREM1, BMP4 and BMP2. We therefore tested for further independent CRC-associated SNPs around these loci (Table S4) by undertaking a pooled analysis of data from 5 CRC GWA studies (UK1, Scotland1, VQ58, CCFR, Australia) and from the UK2 and Scotland2 samples that had been genotyped at 55,000 SNPs with the strongest evidence of association from meta-analysis of UK1 and Scotland1 (Figure S4) [1]. Here, BMP2 is linked to colorectal carcinoma.