Two SNPs in the IL8 genes (rs4073 and rs2227307) were evaluated in patients with systemic sclerosis with (n = 78) or without fibrosing alveolitis (n = 50), those with cryptogenic fibrosing alveolitis (n = 71), and normal healthy subjects in the UK [16]. Here, CXCL8 is linked to idiopathic pulmonary fibrosis.