IL32 and acute respiratory distress syndrome: Such associations between IL-32 SNPs and ALI are not surprising given the multiple cellular populations that express this cytokine and that participate in the pathogenesis of ALI, including macrophages, endothelial, and epithelial cells, as well as the ability of IL-32 to affect inflammatory and other pathways known to mediate pulmonary and extra-pulmonary organ dysfunction occurring with ALI.