Higher levels of C2 and Prkcb (probe 209685_s_at) were associated with a higher lifetime death hazard in males (HR = 1.93 and 5.22, respectively) than in females (HR = 1.30 and 1.31, respectively) and the profile of the latter gene has been observed in colon cancer cell lines [67]. This evidence concerns the gene PRKCB and malignant colon neoplasm.