IL37 and cancer: Marincola goes on to describe why human observation should be held in higher esteem and should not be dismissed as "just descriptive." He also notes: "For example, in animal models, Interleukin-23 can either promote or hamper cancer growth; yet, information about its bio-availability in human cancers and its modality of expression, information that can potentially provide insight into the interpretation of such models, is limited" [160].