Some SNPs also showed a significant effect on survival outcomes, such as RAD51-135 G>C in breast cancer [22], XRCC2 R188H in pancreatic cancer [23], and SNPs of RAD51-135 G>C and XRCC3 T241M in acute myeloid leukemia [24]. The gene discussed is XRCC3; the disease is pancreatic neoplasm.