Macrophage Migration Inhibitory Factor (MIF)” is the key primary chemokine molecule secreted by tumor cells which induces the potent T lymphocyte attractant “Regulated upon Activation, Normal T-cell Expressed, and Secreted (RANTES)” from endothelial cells, which in turn creates a chemotactic gradient for RANTES-receptor bearing T lymphocytes. The gene discussed is MIF; the disease is neoplasm.