Serum alanine aminotransferase (ALT) and alkaline phosphatase (ALP) levels were raised among WT PBC mice compared with WT control mice (48.45 ± 24.69 IU/L versus 27.00 ± 7.78 IU/L, P = .043; 117.74 ± 38.02 IU/L versus 71.17 ± 8.61 IU/L, P = .005), as well as serum total bilirubin (TBIL) levels (1.89 ± 1.12 μmol/L versus 0.24 ± 0.12 μmol/L, P = .001). Here, GPT is linked to primary biliary cholangitis.