Although ALT levels were found to be elevated in all PBC model mice regardless of genotype compared to CXCR3−/− PBC mice, WT PBC mice had higher TBIL level in the serum, but with no statistical significance (2.08 ± 1.19 μmol/L versus 1.68 ± 1.04 μmol/L), as well as ALP level (117.72 ± 38.54 IU/L versus 108.40 ± 28.08 IU/L). The gene discussed is GPT; the disease is primary biliary cholangitis.