During a 4-day period after infection, we observed modest changes in the recovery of innate cells by BAL in GK1.5-treated mice compared to controls that were intermediate in value between mice with primary infection or non-depleted controls (Fig. S3), suggesting local tissue-memory CD4+ T cells may alter the inflammatory cell milieu and play a role in shaping the early innate response. The gene discussed is CD4; the disease is infection.