SHMT2 and B-cell non-Hodgkin lymphoma: We therefore treated the mouse B cell lymphoma cell line Eμ239 with 10 μM Pimi for 24 hours, harvested mRNA and analyzed it using qRT-PCR for the Myc regulated genes Amd1 [39], Aurkb [64], Cad [65], Shmt1, Shmt2 [66] and Srm [39].