表皮生长因子受体(epidermal growth factor receptor, EGFR)与肺癌的发展密切相关,其功能受泛素连接酶(Casitas B-lineage lymphoma, Cbl)家族调节,本研究旨在探讨c-Cbl、Cbl-b和EGFR在非小细胞肺癌(non-small cell lung cancer, NSCLC)组织中的表达及其在预后判断方面的应用价值。. The gene discussed is CBLB; the disease is non-small cell lung carcinoma.