In 2005 three international multidisciplinary consortia have been initiated: Breast Cancer Association Consortium (BCAC), Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) and Ovarian Cancer Association Consortium (OCAC) which are forums of investigators from centers over the world, including International Hereditary Cancer Center in Szczecin. This evidence concerns the gene BRCA1 and breast carcinoma.