These included severalpreviously characterized mechanistic links to complex traits, such asVKORC1 expression and warfarin drug response [51] andSORT1 expression correlations with lipid levels and heartdisease [13],both of which were originally identified using the UW liver panel described here.Additionally, these data support a relationship, which had previously beenspeculated but not shown to exist, between NOD2 expression levelsand leprosy risk [48], and novel hypotheses such as a link between expressionof the uncharacterized C2orf43 gene and prostate cancer risk [52]. This evidence concerns the gene NOD2 and Familial prostate cancer.