As models we used three leukemia/lymphoma cell lines (Figure 4A): Daudi, MRE11 poly(T)11/12; Raji, MRE11 poly(T)11/11, wild type, and DNA repair proficient; and Jurkat, MRE11 poly(T)10/11 known to generate alternative splicing in exon 5 of MRE11 (Figure 4B) and DNA repair deficient [26]. This evidence concerns the gene MRE11 and leukemia.