ADIPOQ and hypertensive disorder: Our current study demonstrated that the SNP variant in ADIPOQ gene could be associated with MetS including HTN component rather than with HTN alone or with MetS excluding HTN component, and that the former phenotype had the lowest plasma adiponectin value, suggesting that MetS could be seen as clusters of metabolic abnormalities, and that ADIPOQ may selectively contribute to some clusters of MetS, especially those with HTN.