MPO and coronary artery disorder: To date, several studies have shown that the -463G/A, -129G/A, -V53F, -A332V, and -638C/A SNPs and MPO levels are risk factors in coronary artery disease (CAD) (Nikpoor et al., 2001; Brennan et al., 2003; Chevrier et al., 2003, 2006; Rutgers et al., 2003; Nicholls and Hazen, 2005; Stefanescu et al., 2008).