According to Kappa statistics, no exact association between these parameters was found in either esophageal or gastric cancers, but only a moderate agreement between amplification of the CCND1 gene and internal or peripheral positioning of this gene within its respective CT in esophageal carcinoma (Kappa = 0.400; p = 0.088). The gene discussed is CCND1; the disease is carcinoma of esophagus.