A population-based study showed that the SNP309 polymorphism in MDM2 and/or the common polymorphism at codon 72 in p53 are associated with predispositions to carcinomas in populations who visited Asian hospitals (Kawaguchi et al., 2000; Hong et al., 2005; Dharel et al., 2006). This evidence concerns the gene TP53 and carcinoma.