Families with Li-Fraumeni (LF; an autosomal dominant cancer-predisposition syndrome) and LF-like families exhibit a nucleotide deletion in the p53 promoter (Attwooll et al., 2002), and mutations have been identified at 15 positions in the p53 promoter in Taiwanese patients with uterine leiomyoma (Hsieh et al., 2007). This evidence concerns the gene TP53 and Lassa fever.