The deletion at positions -346 to -338 (C/EBP site) of p53 in LF (Attwooll et al., 2002) and the mutation at position -250 of p53 in patients with uterine leiomyoma (Hsieh et al., 2007) are located within CpG dinucleotides. This evidence concerns the gene TP53 and Lassa fever.