A similar pattern of expressionhas also been described for the actin-binding protein transgelin (TGLN) [60]; although thismay appear anomalous, it is feasible that these proteins are expressed at highlevels in a small population of basal-like CSCs that are not easily detected byimmunohistochemistry in tumours that display a predominantly luminal(AR+) phenotype. The gene discussed is TAGLN; the disease is neoplasm.